Endocrine Abstracts

Reactive oxygen species (ROS) are involved in the pathogenesis of atherosclerosis. Atrial natriuretic peptide (ANP) reduces thioredoxin in heart failure patients, whereas adrenomedullin, acting as an antioxidant, protects rat cardiomyocytes from infarction and mouse vascular smooth muscle cells from angiotensin II (AII) oxidative effect. Besides AII, aldosterone (Aldo) is also an activator of ROS. Aim of the study was the investigation of the eventual antioxidant effect of ANP...

Background: Vitamin D receptor (VDR) and progesterone receptor (PR) expression have been described before in papillary thyroid carcinoma but data regarding association of this expression with tumour histological characteristics are scarce.Materials and methods: Formalin-fixed, paraffin-embedded specimens from adult patients with papillary thyroid carcinoma (PTC), who underwent total thyroidectomy from 2009 to September 2012 were retrieved. Data regarding...